Epidemiology of Systemic LE and Cutaneous LE

The incidence of systemic lupus erythematosus and cutaneous lupus erythematosus were similar in a predominantly white population.

Patients with cutaneous lupus erythematosus (CLE) frequently have some manifestations of systemic disease and may progress to develop symptoms that fulfill criteria for systemic lupus erythematosus (SLE). In my experience, systemic features are more common in patients with subacute cutaneous LE (SCLE) than in those with chronic LE. Multiple studies of SLE incidence and prevalence have been published, but there are few examining CLE and none comparing the epidemiology of the two diseases.

In a relatively stable and homogeneous population in Olmsted County, Minnesota, these authors studied the incidence and prevalence of these two entities between 1993 and 2005 in 45 patients with SLE and 62 patients with CLE. They found that the incidences of…

Reviewing Author

Jeffrey P. Callen, MD

Disclosures

Consultant / Advisory board XOMA; Eli Lilly; Celgene

Equity Various trust accounts

Editorial boards JAMA Dermatology; UpToDate

Leadership positions in professional societies Association of Professors of Dermatology (President-Elect)