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We have long used stress myocardial perfusion imaging (MPI) to risk-stratify patients with acute chest pain, but computed tomography angiography (CTA) is an increasingly popular alternative. In this single-center U.S. study, investigators randomized 400 patients with acute chest pain who required further imaging to either CTA or MPI.
During the subsequent 1 year, 30 patients in the CTA group (15%) and 32 patients in the MPI group (16%) underwent invasive angiography. Of those who underwent invasive angiography, 15 and 20 patients, respectively, did not undergo revascularization after their angiograms (the primary endpoint for the study); this difference was not significant. Adverse events (e.g., death, nonfatal cardiovascular events) and hea…