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Supraesophageal reflux disease (SERD) is retrograde flow of gastric contents into the laryngopharynx and upper aerodigestive tract. SERD can be associated with throat clearing, cough, asthma, postnasal drainage, sinusitis, laryngopharyngitis, and sleep disturbance.
In a retrospective chart review from a U.S. tertiary allergy clinic, researchers evaluated 235 patients with throat clearing, cough, postnasal drip, or globus sensation who underwent overnight nasopharyngeal pH monitoring. Nasopharyngeal reflux was present in 113 patients; of these, 62 (55%) had reflux only in the supine position, and 47 (42%) had reflux in both upright and supine positions. Among patients with supine-only reflux, 13 underwent repeat monitoring after the head of t…