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Adverse effects of severe hypotension during surgery are quite clear. But what about intraoperative hypertension or marked variability of blood pressure (BP) during surgery? Two studies shed light on this question.
A study from six U.S. veterans' hospitals included data from 18,756 noncardiac surgeries, for which 30-day mortality was 1.8%. As expected, progressively severe intraoperative hypotension was associated with increasing 30-day mortality; the longer the duration of hypotension, the greater the mortality risk. In contrast, progressively higher intraoperative blood pressures were not associated with increasing mortality. These analyses were adjusted for preoperative patient characteristics that confer perioperative risk.
In a study fro…