What Treatments Are Effective for Chronic Sinusitis?

Chronic sinusitis is defined as inflammation of the paranasal sinuses that persists for >3 months. Diagnosis requires two or more of the following symptoms: facial pain, nasal obstruction, nasal discharge, and decreased sense of smell. Additional diagnostic criteria include nasal polyps, middle meatus edema or purulence, and computed tomographic evidence of sinus inflammation. In this systematic review of 12 meta-analyses (>60 randomized, controlled trials), 13 systematic reviews, and 4 randomized, controlled trials that were not included in the meta-analyses, researchers identified the most effective medical therapies for managing chronic sinusitis in adults.

Evidence supports daily use of saline irrigation plus topical intranasal corticost…