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Target Audience: General practitioners, internists, pulmonologists, and infectious diseases specialists
Target Population: Patients with suspected latent Mycobacterium tuberculosis infection in high- and upper-middle–income countries with annual tuberculosis (TB) incidence <100 per 100,000 population
About one third of the world's population is latently infected with M. tuberculosis. These people show immune responses to previously acquired infection but typically have no signs or symptoms of TB disease and are not infectious. Their lifetime risk for developing active TB disease and becoming infectious is estimated to be 5% to 15%, with disease usually developing within…