Rebleeding in Non-Helicobacter, Non-NSAID Peptic Ulcers

Patients with idiopathic ulcers are more likely to rebleed than those with H. pylori– or nonsteroidal anti-inflammatory drug–associated lesions and warrant close surveillance.

Peptic ulcer bleeding (PUB) usually involves lesions induced by Helicobacter pylori infection, nonsteroidal anti-inflammatory drug (NSAID) use, or both. As the prevalence of H. pylori infection decreases in some developed countries, the incidence of idiopathic (i.e., non–H. pylori, non-NSAID) ulcers seems to be increasing.

To examine the influence of ulcer etiology on the clinical characteristics of PUB, investigators retrospectively evaluated the records of 232 patients admitted with PUB to a single hospital in Seoul, South Korea, between 2006 and 2012. Endoscopy was performed within 24 hours, with endoscopic therapy as appropriate. A second endoscopy was performed 48 hours later, with biopsy specimens obtained for histologic testing; patie…

Reviewing Author

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose

Rebleeding in Non-Helicobacter, Non-NSAID Peptic Ulcers

Topics

Reviewing Author