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Insomnia, affecting 10% of the population, is associated with increased risk for depression. Investigators examined possible mechanisms for this association in 62 healthy men and women (39 women; mean age, 26) who demonstrated good sleep and did not have psychiatric or substance use disorders. Participants were randomized to one of three conditions for 3 nights: forced awakenings for 20 minutes each hour and one 60-minute period per night (21 participants; maximum sleep time, 280 minutes); restricted sleep by delaying bedtime so that sleep equaled the total sleep time of a matched participant in the forced awakening condition (17 participants); or usual uninterrupted sleep (24 participants). Sleep architecture was measured by polysomnograph…