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Factors associated with interval colorectal cancer include performance of colonoscopy by a doctor with a low adenoma detection rate (ADR) or low cecal intubation rate, proximal tumor location, microsatellite instability and CpG island methylator phenotype tumor status, family history of colorectal cancer, and positive fecal occult blood test results. Using data from the Taiwanese National Colorectal Screening Program for 2004 through 2009, investigators examined the value of fecal hemoglobin concentration in predicting risk for interval cancer.
Among 29,969 individuals with positive fecal immunochemical test (FIT) results who underwent complete colonoscopy, 162 had interval cancers diagnosed after the index procedure. In multivariable analys…