Safety and Durability of Magnetic Treatment of GERD: Five-Year Follow-Up

Final follow-up of patients who received this surgical intervention revealed continued efficacy and no safety concerns.

In 2012, the U.S. Food and Drug Administration approved the use of a magnetic device that augments the lower esophageal sphincter function as an intervention option for patients with symptomatic gastroesophageal reflux disease (GERD). The current study provides final 5-year data on safety and efficacy of the device, updating a prior report of 3-year follow-up data (NEJM JW Gastroenterol May 2013).

The industry-funded, multicenter study initially comprised 100 patients with partial response to daily proton-pump inhibitors (PPIs) and evidence of pathologic reflux on 24-hour pH monitoring who underwent implantation of the magnetic device. Five-year follow-up data, available for 85 patients, showed that postapproval efficacy endpoints of ≥50% im…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors