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Antibiotic therapy for asymptomatic bacteriuria (AB; bacteria in urine without signs or symptoms of urinary tract infection) is recommended only for pregnant women and men undergoing urologic procedures; nonetheless, treatment of AB is common. A previous study demonstrated that women treated for AB had significantly higher rates of recurrent bacteriuria after 12 months compared with those not receiving antibiotics (NEJM JW Gen Med Nov 1 2012 and Clin Infect Dis 2012; 55:771). Now, in an extension of this study (mean follow-up, 39 months), the same Italian investigators analyzed the results from 550 participants (257 untreated; 293 treated with antibiotics).
Risk for recurrent bacteriuria was 4.4-fold higher in women who received antibiotics …