Does Quantity of Gluten Intake During Infancy Influence Risk for Celiac Disease?

Whether changes in grain products (resulting from hybridization, etc.), timing of introduction of gluten, or the amount of gluten ingested by infants affects the risk for celiac disease are current subjects of research.

In Sweden, infants are commonly fed gluten-containing gruel and porridge after weaning from breast-feeding. To evaluate whether the quantity of gluten consumed before age 24 months is associated with risk for celiac disease, investigators conducted a nested case-control study among 3723 Swedish infants enrolled in a prospective cohort study who had at least one human leukocyte antigen (HLA) genotype associated with high risk for celiac disease. Newborns underwent HLA genotyping and were tested annually for tissue transglutami…