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With the growing use and success of in vitro fertilization (IVF) comes a question: Are more cycles better? To determine the extent to which repeated IVF cycles increase the likelihood of live birth (defined as an infant born alive after 24 weeks' gestation and surviving longer than 1 month), investigators in the U.K. used data from 257,000 ovarian stimulation cycles initiated between 2003 and 2010 in 157,000 women (median age treatment initiation, 35; median duration of infertility, 4 years). Live-birth outcome data were analyzed through June 2012. One IVF cycle was defined as all fresh and frozen embryo transfers resulting from one episode of ovarian stimulation.
The live-birth rate for the first cycle was 29.5%. The cumulative live-birth r…