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Although early recommendations for treatment of gastroesophageal reflux disease (GERD) emphasized lifestyle modifications, the three most-recent national guidelines (Canadian Association of Gastroenterology, 2005; American Gastroenterological Association, 2008 [NEJM JW Gastroenterol Jan 2009 and Gastroenterology 2008; 135:1383]; American College of Gastroenterology, 2013 [NEJM JW Gastroenterol May 2013 and Am J Gastroenterol 2013; 108:308]) minimize their importance, citing mixed results on their effectiveness.
To reassess the evidence for efficacy of lifestyle interventions in GERD treatment, researchers conducted a comprehensive systematic review including 15 original studies and two previous systematic reviews. Key findings for various in…