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Venous thromboembolism (VTE) prevention guidelines recommend risk assessment of inpatients for thrombosis and bleeding upon hospital admission (NEJM JW Gen Med Mar 15 2012 and Chest 2012; 141:7; Chest 2012; 141[2 Suppl]:e195S). The International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) investigators have developed assessments for both clot and bleeding risks, however their bleeding risk score (IMPROVE BRS) lacks external validation.
Investigators prospectively calculated IMPROVE BRS for approximately 1700 adult inpatients (78% in medical wards; 22% in medical intensive care unit or coronary care unit) admitted to a U.S. army medical center during 18 months; patients admitted for bleeding and those who received treatmen…