In an observational study, prestroke aspirin use was associated with lower stroke severity from large-artery atherosclerosis but not small-vessel occlusion or cardioembolism.
Aspirin reduces the risk for recurrent ischemic stroke. Even in cases where aspirin does not prevent stroke entirely, it might reduce infarction size. However, prior studies have reported conflicting findings about whether prestroke aspirin use is associated with lower stroke severity. Therefore, researchers in South Korea examined the association between prestroke aspirin use and clinical stroke severity in a partially manufacturer-sponsored study.
The researchers retrospectively identified patients who were prospectively enrolled in a multicenter registry between 2008 and 2012 after having an ischemic stroke caused by large-artery atherosclerosis, small-vessel occlusion, or cardioembolism. Patients with prior use of antithrombotics other t…
Reviewing Author
DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)
DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)