Mechanical Thrombectomy for Acute Ischemic Stroke: Weight of the Evidence

A meta-analysis finds support for a benefit among patients in recent clinical trials.

In 2015, several high-profile acute stroke trials were published that demonstrated the value of endovascular acute stroke intervention. Now, researchers have performed a systematic analysis of trials evaluating mechanical thrombectomy between 5 and 12 hours after onset of acute ischemic stroke. For this analysis, thrombectomy devices had to be used in the trials (as opposed to intra-arterial thrombolysis alone), 90-day follow-up was provided, and at least some of the control group patients received intravenous tissue plasminogen activator (TPA). Overall, ten studies were identified, seven of them in the “recent era” in which stent retrievers were predominantly used. Five of the seven studies have been published; two studies have reported re…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Mechanical Thrombectomy for Acute Ischemic Stroke: Weight of the Evidence

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Reviewing Author