Prognostic Accuracy in Patients with Suspected Coronary Artery Disease

In predicting major cardiovascular events in patients with suspected coronary heart disease, CMR is superior to SPECT in a 5-year follow-up study.

In the prospective single-center study, CE-MARC (NEJM JW Cardiol Apr 2012 and Lancet 2012; 379:453), cardiovascular magnetic resonance (CMR) had greater diagnostic accuracy than myocardial perfusion imaging with single-photon emission computed tomography (SPECT) for the detection of coronary artery disease (CAD) in patients with suspected stable angina and at least one major cardiovascular risk factor. Now, researchers report 5-year follow-up findings of major adverse cardiovascular events (MACEs).

By protocol, the 752 patients were scheduled for CMR and SPECT, followed by coronary angiography within 4 weeks; 5-year follow-up data were available for 99% (median duration, 80.7 months). Among the 628 patients with CMR, SPECT, and angiographic …

Reviewing Author

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Prognostic Accuracy in Patients with Suspected Coronary Artery Disease

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Reviewing Author