Because some uropathogens are less likely to cause pyuria, a urine culture is necessary to diagnose urinary tract infection.
Pyuria is absent in an estimated 10% of urines that are culture-positive for a urinary pathogen. In the current retrospective study, researchers assessed which urinary pathogens were most often associated with an absence of pyuria in children with symptoms of a urinary tract infection (UTI).
The study comprised 1181 patients aged <18 years presenting to a single emergency department between 2007 and 2013 with symptoms of a UTI. All patients had a single urinalysis and positive urine culture within 3 hours of each other. Most patients were girls (89%) and white (80%), and their median age was 23 months.
Pyuria was present in 87% of patients and absent in 13%. Those without pyuria were significantly less likely to have Escherichia coli as a pat…
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DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)