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Spontaneous subarachnoid hemorrhage (SAH) is uncommon but can be fatal; the diagnosis is often at the front of emergency physicians' minds when evaluating a patient with sudden-onset headache. The mainstay of diagnosis has been the combination of an unenhanced computed tomography (CT) scan followed, if negative, by a lumbar puncture (LP; NEJM JW Emerg Med Jan 2013 and Acad Emerg Med 2012; 19:1134). However, the improved sensitivity of modern CT technology may obviate the need for LP, especially in the initial hours of the disease.
Researchers performed a high-quality meta-analysis focused on the diagnostic accuracy of history, physical examination, LP, CT, and clinical decision rules for SAH. Among 22 studies included in the analysis, the av…