There were no major outcome differences between patients randomized to immediate, whole-body computed tomography and those who underwent targeted imaging.
Retrospective studies in European cohorts have raised the possibility that immediate, whole-body computed tomography (CT) can decrease mortality for patients with severe trauma (NEJM JW Emerg Med May 2009 and Lancet 2009 Mar 24; [e-pub]). These authors randomized 1403 Dutch and Swiss patients with severe trauma to immediate whole-body CT (non-contrast exam of head and neck, followed by split-bolus, contrast-enhanced CT of the chest, abdomen, and pelvis) or standard imaging (focused assessment with sonography in trauma [FAST] exam plus plain films of the chest and pelvis, followed by targeted CT at the discretion of the trauma team, which included trauma surgeons but no emergency physicians).
Among 1083 patients included in the primary analys…
Reviewing Author
DisclosuresRoyaltiesUpToDate
Grant/Research SupportEunice Kennedy Shriver National Institute of Child Health and Human Development; MINDSOURCE
Editorial BoardsThe Quarterly Update: Reviews of Current Child Abuse Medical Research; Child Abuse & Neglect: The International Journal
Leadership Positions in Professional SocietiesThe Helfer Society (Executive Committee Member)
DisclosuresRoyaltiesUpToDate
Grant/Research SupportEunice Kennedy Shriver National Institute of Child Health and Human Development; MINDSOURCE
Editorial BoardsThe Quarterly Update: Reviews of Current Child Abuse Medical Research; Child Abuse & Neglect: The International Journal
Leadership Positions in Professional SocietiesThe Helfer Society (Executive Committee Member)