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Does elevated exposure to environmental microorganisms in childhood result in lower risk for atopy later in life? To address this question, researchers assessed whether thumb-sucking or nail-biting habits in children were associated with reduced rates of atopic sensitization, asthma, or hay fever in a prospective birth-cohort study of New Zealand residents. Thumb-sucking and nail-biting were assessed via parental questionnaire at ages 5, 7, 9, and 11 years. Skin-prick testing for selected antigens was conducted in most participants at ages 13 and 32 years, at which time asthma and hay fever were self-reported.
Among 1013 participants, having one or both habits (prevalence, 31%) was associated with reduced risk for atopic sensitization at age…