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The company 23andMe offers consumers what some have called “recreational genetics” — genetic analyses with associated disease information, based on genotyping of saliva samples collected by consumers at home. In a study partially funded by a pharmaceutical company, investigators mined 23andMe data to seek depression-related single nucleotide polymorphisms (SNPs).
Based on data from 75,607 consumers with self-reported depression and 231,747 not reporting depression, five SNPs positive for depression were found. Three of these were also found in a 23andMe replication sample (45,773 depressed consumers and 106,354 nondepressed consumers). Similar results were found in subsamples of consumers who reported receiving antidepressants or other psych…