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Acute respiratory distress syndrome (ARDS) can complicate major trauma and is associated with high mortality. Case reports and small case series have reported improved survival when extracorporeal membrane oxygenation (ECMO) is used in trauma patients with severe ARDS.
These investigators conducted a retrospective cohort study of trauma patients with severe ARDS who were intubated during 1 year before and 1 year after the initiation of an ECMO program at a single level 1 trauma center. Severe ARDS was defined as a PaO2/FIO2 ratio <100 along with bilateral pulmonary infiltrates. Patients in the pre-ECMO group had ventilator management guided by the ARDSnet protocol. Patients in the intervention group were treated with ECMO if they had persist…