Predictors of Early Cerebrovascular Events After TAVR

Events within 30 days are predicted by female sex, chronic kidney disease, and new atrial fibrillation.

Although experience and new transcatheter aortic valve replacement (TAVR) systems have reduced the rate of periprocedural cerebrovascular events (CVE: stroke and transient ischemic attack), identification of risk factors for these potentially devastating events could lead to better prevention strategies. Investigators have now performed a meta-analysis of 64 studies with 72,318 patients (range of mean age, 79–84; men, 48%); 28 studies had data on baseline predictors and 41 had data on procedural factors. The incidence of CVE was 3.3% (median, 4%).

Baseline predictors of CVE by 30 days after TAVR included a lower risk for men (risk ratio [RR], 0.82) and a higher risk for patients with chronic kidney disease (RR, 1.29). Among procedural factor…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI

Leadership Positions in Professional SocietiesHeart Valve Collaboratory (Scientific Committee Member, Chair of the Publications Committee)