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Several groups have developed decision tools — each with limitations — to predict adverse outcomes in patients with syncope. This latest effort is a prospective cohort study that involved 4030 adults who presented to six Canadian emergency departments (EDs) within 24 hours after syncopal events.
During 30 days of follow-up, serious adverse events (including death and several specified cardiac and noncardiac events) occurred in 3.6% of patients. Using multivariable analysis and additional statistical techniques to confirm the validity of the selected predictive variables, the researchers derived a risk score (range, −3 to +11) based on nine clinical predictors.* Risk for a serious adverse event ranged from 0.4% (in patients with score of −3) …