Is Calcium Supplementation Associated with Higher Cardiovascular Risk?

A new guideline suggests that dietary and supplemental calcium intakes lower than 2500 mg daily don't affect CV risk.

Sponsoring Organizations: National Osteoporosis Foundation; American Society for Preventive Cardiology

Target Audience: Primary care providers

Background

Previous meta-analyses of randomized trials suggested an association between calcium supplementation and excess risk for myocardial infarction and stroke (NEJM JW Gen Med Oct 1 2010 and BMJ 2010; 341:c3691; NEJM JW Gen Med Jun 1 2011 and BMJ 2011; 342:d2040). However, this finding has not been observed consistently. To reconcile these conflicting findings, researchers conducted an updated systematic review and meta-analysis of evidence on effects of calcium intake from diet and supplements, alone or with vitamin D, on risk for cardiovascular (CV) disease in generally healthy adults. Four rand…

Reviewing Author

Jamaluddin Moloo, MD, MPH

Disclosures

Grant / Research supportColorado Health Foundation

Jamaluddin Moloo, MD, MPH

Disclosures

Grant / Research supportColorado Health Foundation

Is Calcium Supplementation Associated with Higher Cardiovascular Risk?

Topics

Background

Reviewing Author