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Acute pancreatitis (AP) has increased in the past decade and accounts for over 275,000 annual hospital admissions in the U.S. and estimated medical costs of $2.5 billion. The current review by three noted experts focuses on the most recent practice changes and addresses ongoing issues and questions in management of AP. Noteworthy points are as follows:
Morbid obesity and type II diabetes mellitus are independent risk factors for AP.
Patients with vague symptoms and minimal amylase/lipase elevation (<3 times the upper limit of normal) should not receive a diagnosis of AP.
The most useful predictors of severe disease are elevations at admission and during the following 24 to 48 hours of the following: hematocrit (>44%), blood urea nitrogen (>20 …