Candida auris Emerging Worldwide, Multidrug Resistant, and Lethal

A yeast not identified before 2009 has emerged on several continents almost simultaneously and carries a high mortality.

The first known isolation of Candida auris, from an external auditory canal in Japan, was followed soon after by 15 otitis media and 3 blood stream infections (BSIs) with this organism in Korea. In the intervening years, C. auris fungemia has been reported in India, South Africa, Kuwait, South America and, in 2013, in the U.S. (NEJM JW Infect Dis Jan 2017 and MMWR Morb Mortal Wkly Rep 2016; 65;1234). The infections' resistance to antifungal agents and high mortality have been noted.

These authors analyzed the epidemiology, antifungal susceptibility, and clinical determinants of C. auris infection using isolates from 54 patients; clinical information was available on 41 of these patients. Although specific risk factors for C. auris infection …

Reviewing Author

Stephen G. Baum, MD

Disclosures

Consultant/Advisory BoardClinical Infectious Diseases

RoyaltiesUpToDate

Editorial BoardsMedical Letter

Stephen G. Baum, MD

Disclosures

Consultant/Advisory BoardClinical Infectious Diseases

RoyaltiesUpToDate

Editorial BoardsMedical Letter

Candida auris Emerging Worldwide, Multidrug Resistant, and Lethal

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Reviewing Author