Predictive Value of the 6-Minute Walk Test in Children with Cystic Fibrosis

A higher score predicted lower risk for acute hospitalization during 4 subsequent years.

In children with cystic fibrosis (CF), acute respiratory deterioration resulting in hospitalization is associated with significant morbidity and negative impact on quality of life.

To evaluate possible associations between common functional test scores in CF and risk for acute hospitalization, researchers in Italy conducted a 5-year longitudinal study of 26 children with CF and mild lung impairment (mean age in year 1, 10.2 years). Patients were assessed annually using pulmonary function studies measuring forced expiratory volume in 1 second (FEV₁) and forced expiratory flow between 25% and 75% of forced vital capacity (FEF), respiratory muscle strength tests, and the 6-minute walk test (6MWT). The 6MWT involves walking at maximal speed back…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Predictive Value of the 6-Minute Walk Test in Children with Cystic Fibrosis

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Reviewing Author