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Current strategies for reducing the burden of early-onset Group B streptococcal (GBS) disease include universal screening of third-trimester pregnant women. While antibiotic prophylaxis for GBS carriers is not indicated before cesarean delivery in the absence of labor or ruptured membranes, the CDC recommends screening all women regardless of planned delivery mode. Investigators conducted a cost-effectiveness analysis to determine if this practice remains valuable among women planning to undergo elective repeat cesarean delivery.
In the “base case” scenario (using literature-derived estimates for prevalence of GBS carriage, likelihood of labor before scheduled cesarean, and morbidity from GBS disease), screening all women prior to planned re…