The Frontier of Neonatology: The Limits of Viability

Survival without neurodevelopmental impairment for periviable infants born at 23–24 weeks' gestation improved from 2000 to 2011.

Extreme prematurity is a major contributor to neonatal mortality and neurodevelopmental morbidity in the U.S. There continues to be concern about outcomes for infants born at the limits of viability (≤24 weeks' gestation).

Investigators examined survival and neurodevelopmental outcomes for 4227 neonates born at 22 to 24 weeks' gestation at 11 Neonatal Research Network centers. Outcomes at 18 to 22 months of corrected age were compared among participants in three birth-year periods: 2001–2003, 2004–2007, and 2008–2011.

Overall, survival without neurodevelopmental impairment increased significantly from 16% in 2000–2003 to 20% in 2008–2011. This was primarily due to a significant reduction in mortality between the two periods for infants born a…

Reviewing Author

Robin Steinhorn, MD

Disclosures

Consultant/Advisory BoardActelion Pharmaceuticals

Editorial BoardsJournal of Pediatrics

Leadership Positions in Professional SocietiesAmerican Pediatric Society (President); American Board of Pediatrics (Board of Directors)

Robin Steinhorn, MD

Disclosures

Consultant/Advisory BoardActelion Pharmaceuticals

Editorial BoardsJournal of Pediatrics

Leadership Positions in Professional SocietiesAmerican Pediatric Society (President); American Board of Pediatrics (Board of Directors)

The Frontier of Neonatology: The Limits of Viability

Topics

Reviewing Author