Antithrombotic Medications and Risk for Subdural Hematoma

A case-control study shows an increased SDH risk, especially with vitamin K antagonists and when more than one antithrombotic is used.

With the aging of the population, an increasing percentage of the population is expected to receive antithrombotic medications. Antiplatelet agents and anticoagulants are frequently used for prevention of atherosclerotic events or stroke. Researchers conducted a case-control study in Denmark to evaluate the association of antithrombotic medication use with subdural hematoma (SDH). In the study, 10,010 patients (age range, 20–89; mean age, 69.2; 35% women) with a diagnosis of SDH were compared with 400,380 individuals from the general population. Odds ratios (ORs) were calculated using logistic regression models. In the patients with an SDH, 47.3% were taking antithrombotic medication. SDH frequency was higher with than without antiplatelet …

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Antithrombotic Medications and Risk for Subdural Hematoma

Topics

Reviewing Author