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Most cigarette smokers do not stay abstinent after treatment. Evidence suggests that extending cognitive-behavioral therapy (CBT) improves abstinence rates and that CBT improves the efficacy of pharmacotherapy and may even surpass it. The current researchers conducted the first-ever study directly comparing a shorter course of CBT to a longer one.
All 219 participants received manual-based CBT focusing on self-regulatory skills to avoid smoking relapse plus pharmacotherapy (bupropion and nicotine replacement). After 10 weeks, in an adaptive-treatment approach, pharmacotherapy was stopped, extended, or switched to varenicline, based on smoking status, depression, and craving symptoms. All participants received 26 weeks of CBT initially. The g…