Moderate-Intensity Exercise in Hypertrophic Cardiomyopathy: Could It be Beneficial?

In a small randomized trial, a structured program improved exercise capacity without evidence of major adverse consequences.

Making recommendations for activity regimens for patients with hypertrophic cardiomyopathy (HCM) is challenging. On one hand, HCM is associated with sudden cardiac death in competitive athletes. On the other hand, individuals with HCM generally are sedentary and have impaired peak oxygen consumption (VO₂), which may have deleterious effects. Despite the consensus against competitive sports in this population, non–evidence-based international guideline recommendations are conflicting about moderate-intensity exercise. This randomized, controlled trial was designed to assess the impact of moderate-intensity exercise on exercise capacity in 136 patients with HCM (mean age, 50; 42% women, 17% with resting left ventricular outflow tract gradient…

Reviewing Author

Frederick A. Masoudi, MD, MSPH, FACC, FAHA

Disclosures

Consultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research

Grant/Research SupportNational Heart, Lung, and Blood Institute

Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)

Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)

Frederick A. Masoudi, MD, MSPH, FACC, FAHA

Disclosures

Consultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research

Grant/Research SupportNational Heart, Lung, and Blood Institute

Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)

Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)

Moderate-Intensity Exercise in Hypertrophic Cardiomyopathy: Could It be Beneficial?

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Reviewing Author