Benefits of Endovascular Treatment for Acute Ischemic Stroke Are Sustained Long-Term

Improvements in functional outcomes at 2 years were similar to those previously reported in the MR CLEAN trial at 90 days.

For ischemic strokes that are caused by a proximal anterior-circulation large vessel occlusion, several clinical trials have demonstrated improved short-term (90-day) functional outcomes with endovascular treatment. Now, investigators report 2-year clinical outcomes for patients that were enrolled in the partially manufacturer-funded Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN; NEJM JW Neurol Dec 17 2014 and N Engl J Med 2015; 372:11).

In this extended follow-up study, 2-year data were available for 391 (78.2%) of the 500 patients who underwent randomization in MR CLEAN; mortality information was available for 459 (91.8%). The distribution of functional outcomes (as m…

Reviewing Author

Anthony S. Kim, MD

Disclosures

Grant/Research SupportNIH/National Institute of Neurological Disorders and Stroke; NIH/National Center for Advancing Translational Sciences

Anthony S. Kim, MD

Disclosures

Grant/Research SupportNIH/National Institute of Neurological Disorders and Stroke; NIH/National Center for Advancing Translational Sciences

Benefits of Endovascular Treatment for Acute Ischemic Stroke Are Sustained Long-Term

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Reviewing Author