The Beginning of the End for Bioresorbable Coronary Scaffolds?

A worrying increase is seen in thrombosis risk with bioresorbable coronary scaffolds compared to standard metallic stents in a large randomized controlled trial.

Coronary angioplasty was performed for years by simple balloon angioplasty, which brought problems of recoil and high restenosis rates. The invention of stents dramatically reduced the restenosis risk but at the price of stent thrombosis. Therefore, the concept of bioresorbable vascular scaffolds was intriguing, and the first one (ABSORB) was widely used, despite scarce data. Now, researchers have reported results from one of the largest randomized, controlled trials evaluating bioresorbable scaffolds.

The industry-funded trial randomized 1845 patients to percutaneous coronary intervention with an everolimus-eluting bioresorbable scaffold or an everolimus-eluting metallic stent (stable coronary artery disease, 40% of patients; ST-segment ele…

Reviewing Author

Pascal Meier, MD

Disclosures

Editorial BoardsOpen Heart

Leadership Positions in Professional SocietiesEuropean Society of Cardiology (Communication Committee); European Association of Percutaneous Cardiovascular Interventions (Chair, Web & Communication Committee)

Pascal Meier, MD

Disclosures

Editorial BoardsOpen Heart

The Beginning of the End for Bioresorbable Coronary Scaffolds?

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Reviewing Author