Celiac Disease and Anorexia Nervosa: Are They Connected?

A bidirectional association was observed in Swedish girls and women.

Anorexia nervosa (AN) has been linked to celiac disease (CD) in case reports. To test this possible association further, investigators conducted a retrospective, case-control, cohort study involving 17,959 women with CD (median age at diagnosis, 28 years; range, 6–52 years) and 89,379 age- and sex-matched, population-based controls identified in the Swedish national health registry.

From 1987 through 2009, during more than 1 million person-years of follow-up, patients with a biopsy-proven diagnosis of CD were more likely than controls to have later AN (27 vs. 18/100,000 person-years; hazard ratio, 1.46). Also, patients with AN were more likely than controls to have later CD (odds ratio, 2.18). In subgroups of patients with mucosal inflammati…

Reviewing Author

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

F. Bruder Stapleton, MD

Disclosures

Consultant/Advisory BoardCareer Physician

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesAmerican Society of Pediatric Nephrology Foundation (Chair)

Celiac Disease and Anorexia Nervosa: Are They Connected?

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Reviewing Author