Suppressive Antibiotic Treatment for Prosthetic Joint Infection in the Elderly

In patients older than 75, 2-year survival without treatment-related side effects or death was 61% with suppressive therapy.

Standard management of prosthetic joint infection (PJI) usually requires surgical device exchange and antibiotic therapy. This approach is sometimes impossible in elderly patients with high perioperative risks. For them, prolonged suppressive antibiotic therapy (PSAT) is the only option for preventing infection exacerbation, but little is known about the long-term outcome of this unpopular strategy.

Researchers conducted a retrospective cohort study of 136 patients (median age, 83; 47% women) who received PSAT for PJI at 77 centers (infectious diseases, orthopedics, internal medicine, and geriatrics departments) between 2009 and 2014. Infections involved the hip, knee, or shoulder in 60%, 39%, and 1% of cases, respectively. Reasons for PSAT …

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Suppressive Antibiotic Treatment for Prosthetic Joint Infection in the Elderly

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Reviewing Author