Guidance on Use of MRI in Diagnosis and Management of Primary Sclerosing Cholangitis

Target Audience: Hepatologists, gastroenterologists, radiologists

Background and Objective

Magnetic resonance imaging/magnetic resonance cholangiopancreatography (MRI/MRCP) is the preferred noninvasive modality in evaluating patients with suspected primary sclerosing cholangitis (PSC). A working group has developed guidance statements on the use of MRI/MCRP in diagnosis and management of PSC, based on recent literature and their own expertise.

Key Recommendations

• Use MRCP as the first diagnostic imaging modality for suspected PSC. MRCP alone or with contrast (i.e., MRI/MRCP) is sufficient.

• Perform MRI/MRCP prior to endoscopic retrograde cholangiopancreatography or percutaneous cholangiogr…