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Deep brain stimulation for Parkinson disease, essential tremor, and other neuropsychiatric indications has provided an important treatment for tens of thousands of patients. The treatment requires brain surgery and carries a small but clinically relevant risk. Now, researchers have tackled the complex issue of precisely applying deep brain stimulation to areas beyond the surface of the brain.
The technique is referred to as temporal interference (TI). TI delivers multiple currents at high frequency. The high frequency preserves the normal firing of superficial brain cells and allows direct access to deep structures. The authors used two current sources, each set to a different frequency. The deep interference between the two separated electr…