Perfusion Deficits and Short-Term Radiologic Infarction Following TIA

Perfusion deficits at baseline were associated with new infarcts 1 week later.

The classic view of a transient ischemic attack (TIA) as a focal neurovascular deficit lasting less than 24 hours is now viewed as too simplistic. In the hours and days after a TIA or minor stroke, modern neuroimaging shows dynamic changes in blood flow and progression to brain infarction.

To examine the association between perfusion-weighted imaging (PWI) and outcomes 1 week after TIA, investigators studied 64 patients (mean age, 64; 45% women) with a recent TIA or minor stroke with brain magnetic resonance imaging (MRI), including both diffusion-weighted imaging (DWI) and PWI. Patients were initially scanned a mean of 5 hours after symptom onset, then had follow-up imaging an average of 6 days after the initial symptoms.

None of the patient…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Perfusion Deficits and Short-Term Radiologic Infarction Following TIA

Topics

Reviewing Author