Loading...
Over the last several years, research from large prospective cohort studies, such as the current one from the Drug-Induced Liver Injury (DILI) Network, has characterized the presentation and outcomes of patients with DILI, but not across racial and ethnic groups.
Using data from subgroups of 144 non-Hispanic black or African-American patients and 841 non-Hispanic white or Caucasian patients with suspected DILI who were enrolled between 2004 and 2016, researchers compared causative agents, severity of liver injury, and outcomes (transplantation and liver-related death) across groups. Patient race and ethnicity were self-identified.
Among the antimicrobials leading to DILI, amoxicillin/clavulanate was more common among Caucasians than among Afr…