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Seizures in critically ill patients are common but often lack clinical signs. Being able to detect and thus to effectively treat these subclinical seizures should improve outcomes in some patients. Continuous electroencephalography (CEEG) can detect these seizures but is costly, particularly in hospital technical resources and expert physician time. To determine how to optimize CEEG use, researchers examined observational data from two major tertiary medical centers on 665 patients with at least 24 hours of CEEG recording and without postanoxic coma.
The investigators controlled for differences in treatment and duration of CEEG recording by using a multistate survival analysis to model time-dependent predictions of seizure risk over a 72-hou…