CABG in Patients with Carotid Disease: What Is the Best Operative Strategy?

Despite this study's limitations, its findings suggest that performing carotid endarterectomy simultaneously with coronary artery bypass grafting provides no advantage over CABG alone.

The optimal operative strategy for patients in need of coronary artery bypass grafting (CABG) who have concomitant severe carotid artery disease is unknown. Investigators conducted a randomized trial in Germany and the Czech Republic comparing outcomes with simultaneous CABG and carotid endarterectomy (CEA) to those with CABG alone.

Significant carotid artery stenosis was defined as ≥80%. The trial, which had an initial planned size of 1160, was terminated early because of insufficient recruitment. The final enrollment, occurring between 2010 and 2014, was 129 patients.

In the intent-to-treat analysis, the primary composite endpoint of any stroke or death from any cause within 30 days postsurgery occurred in 18.5% of the simultaneous-surgery …

Reviewing Author

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

CABG in Patients with Carotid Disease: What Is the Best Operative Strategy?

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Reviewing Author