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As the obesity epidemic escalates, its consequences in reproductive-aged women assume increasing importance. To assess the effects of extreme obesity on pregnancy outcomes, investigators at two Minnesota hospitals performed a retrospective study of women with body-mass index (BMI) ≥60 kg/m2 at delivery compared with those having BMI of 30 to 39, 40 to 49, or 50 to 59.
Rates of maternal complications and neonatal morbidities were substantially higher in women with BMI ≥60 than in any of those with BMIs between 30 and 59 (). Composite neonatal morbidity was significantly more likely among newborns whose mothers had BMI ≥60 compared with those in the reference cohort (BMI 30–39; adjusted odds ratio, 4.5).