Adenoma Detection Rate Predicts Risk for Metachronous Advanced Neoplasia

The adenoma detection rate (ADR) has been shown to predict the risk for interval cancer after colonoscopy. Improvements in ADR have been associated with lower risk for metachronous cancer.

Researchers in Korea retrospectively assessed predictors of advanced neoplasia (AN), a surrogate for cancer, at 3- to 5-year follow-up in over 7000 individuals with either no or low-risk adenomas (1–2 tubular adenomas <1 cm with low-grade dysplasia) detected at screening colonoscopy. Thirty-one gastroenterologists performed a median of approximately 300 examinations each.

In multivariate analysis, predictors of AN at follow-up included the ADR of the endoscopist at screening (odds ratio, 0.97) and the ADR of the endoscopist at follow-up (OR, 1.07). The high…