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Some studies suggest that cannabinoids may help treat seizure disorders and chemotherapy-induced nausea and vomiting in children, but the data are very limited.
To better characterize the evidence to date, investigators conducted a systematic review of articles published between 1948 and 2017. Twenty-two studies involving 795 participants met inclusion criteria. Only 5 studies were randomized, controlled trials; the remainder were retrospective chart reviews (5), case reports (5), open-label trials (4), parent surveys (2) and 1 case series. Only 9 studies included more than 20 patients. The most commonly studied indications were seizure disorders (11 studies) and chemotherapy-induced nausea and vomiting (CINV; 6 studies). Results were as fol…