Using CT to Identify Pulmonary Hypertension Secondary to Left Heart Disease

Cardiac chamber volume, calculated from chest computed tomography, was used as a noninvasive discriminator.

Pulmonary hypertension can be a result of left-sided heart disease (WHO group 2) or of intrinsic abnormalities of the pulmonary vasculature. In this study of 114 patients with pulmonary hypertension who underwent both right heart catheterization (RHC) and chest computed tomography (CT) with volumetric analysis of cardiac chambers, 27 (24%) were classified as WHO group 2 based on wedge pressure >15 mm Hg as determined by RHC.

Group 2 patients had significantly larger left heart volumes and smaller right ventricular volumes than did non–group 2 patients. In adjusted analyses, left atrial volume was an independent predictor of group 2 patients and left atrial enlargement identified those patients (area under the curve, 0.92).

Reviewing Author

Kirsten E. Fleischmann, MD, MPH

Disclosures

Grant/Research SupportNational Institutes of Health

Leadership Positions in Professional SocietiesAmerican College of Cardiology/American Heart Association

Kirsten E. Fleischmann, MD, MPH

Disclosures

Grant/Research SupportNational Institutes of Health

Leadership Positions in Professional SocietiesAmerican College of Cardiology/American Heart Association

Using CT to Identify Pulmonary Hypertension Secondary to Left Heart Disease

Topics

Reviewing Author