Significant Benefit Associated with Accepting an Organ from an Increased-Risk Donor

Patients who accepted an IRD kidney had lower 5-year mortality than those who declined IRD organs.

The Public Health Service has defined behavioral criteria that identify potential donors as increased-risk donors (IRDs) at higher risk for recent infection with hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV) (Public Health Rep 2013; 128:247) These donors may be in the “window period” when donor screening assays are negative but transmission of virus to recipients is possible. National policy requires that potential recipients of IRD are consented regarding the risk for donor to recipient transmission. In part as a result of the opioid epidemic, up to 25% of potential donors are IRD (Am J Transplant 2015; 15: 3215).

Researchers have now used a national database to compare outcomes of 104,988 potential kidney rec…

Reviewing Author

Daniel Kaul, MD

Disclosures

Grant/Research SupportNobelpharma; Pfizer

Leadership Positions in Professional SocietiesAmerican Society of Transplantation (Program Committee)

Daniel Kaul, MD

Disclosures

Grant/Research SupportNobelpharma; Pfizer

Leadership Positions in Professional SocietiesAmerican Society of Transplantation (Program Committee)

Significant Benefit Associated with Accepting an Organ from an Increased-Risk Donor

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Reviewing Author